By: AS Fauchi and L Lambert
17 November 2010
In a review article appearing in the New England Journal of Medicine, scientists at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, examine research under way to address the limitations of currently available influenza vaccines and develop more efficient and reliable strategies to make vaccines to protect against seasonal as well as pandemic influenza. Although licensed seasonal flu vaccines safely and effectively protect most people who receive them from illness and death, the degree of protection varies depending on how well the circulating virus strains and those in the vaccine match. A vaccine recipient’s age and health status also can affect the effectiveness of influenza vaccination.