Prevalence Mohammadreza Haghshenas1, Tahereh Golini-moghaddam2, Alireza Rafiei1, Omid Emadeian2, Ahmad Shykhpour1 and G Hossein Ashrafi3* Abstract Background Cervical cancer is the greater cause of cancer death in women in many developing countries. Persistent infection with human papilloma virus (HPV), primarily high risk types 16 and 18, is recognized as a causal and essential factor for the development of cervical cancer. We […]
HPV prevalence and genetic predisposition to cervical cancer in Saudi Arabia
Genetic Predisposition Corresponding author: Ghazi Alsbeih galsbeih@kfshrc.edu.sa Background Cervical cancer incidence is low in Saudi Arabian women, suggesting low prevalence to HPV infection due to environmental, cultural and genetic differences. Therefore, we investigated HPV prevalence and genotype distribution in cervical cancer as well as the association with 9 genetic single nucleotide polymorphisms (SNPs): CDKN1A (p21) C31A, TP53 C72G, ATM G1853A, HDM2promoter T309G, HDM2 A110G, LIG4 A591G, XRCC1 G399A, XRCC3 C241T and TGFβ1 T10C, […]
Topological conformational changes of human papillomavirus (HPV) DNA bound to an insoluble aluminum salt—A study by low temperature PCR
Author(s): Sin Hang Lee ABSTRACT A low temperature (LoTemp®) polymerase chain reaction (PCR), conducted at cycling temperatures not to exceed 85℃and catalyzed by a novel highly processive HiFi® DNA polymerase with proofreading function, was used to study the topological conformational changes of the human papillomavirus (HPV) L1 gene DNA fragments bound to the insoluble amorphous aluminum […]
Death after Quadrivalent Human Papillomavirus (HPV) Vaccine: Causal or Coincidental?
Lucija Tomljenovic1* and Christopher A Shaw1,2,3 1Department of Ophthalmology and Visual Sciences, University of British Columbia, Canada 2Program in Experimental Medicine, University of British Columbia, Canada 3Program in Neuroscience, University of British Columbia, Canada Abstract: Background: The proper understanding of a true risk from vaccines is crucial for avoiding unnecessary adverse reactions (ADRs). However, to […]
Human papillomavirus genotype distribution among French women with and without cervical abnormalities.
Int J Gynaecol Obstet. 2011 Aug;114(2):116-9. Epub 2011 Jun 12. Casalegno JS, Benchaib M, Le Bail Carval K, Piaton E, Mathevet P, Mekki Y. Source: Laboratory of Virology, Femme-Mère-Enfant Hospital, Bron, France. Abstract OBJECTIVE: To assess human papillomavirus (HPV) prevalence and distribution among French women with normal and pathologic cytology findings. METHODS: A genomic DNA microarray assay enabling the detection […]
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