Reprinted from Australian Family Physician Vol. 38, No. 12, December 2009 Stella Heley BA(Hons), MBBS, FAChSHM, is Senior Liaison Physician, Victorian Cytology Service, Melbourne, Victoria. sheley@ vcs.org.au Julia Brotherton BMed(Hons), MPH(Hons), GradDipAppEpi, FAFPHM, is an epidemiologist, National HPV Vaccination Program Register, Victorian Cervical Cytology Registry, Victorian Cytology Service, Melbourne, Victoria. Background Worldwide, cervical cancer affects […]
ACUTE DISSEMINATED ENCEPHALOMYELITIS FOLLOWING VACCINATION AGAINST HUMAN PAPILLOMA VIRUS
Neurology
B. Wildemann, S. Jarius, M. Hartmann, J. U. Regula and C. Hametner
Neurology 2009;72;2132-2133
DOI: 10.1212/WNL.0b013e3181aa53bb
We report a case of severe encephalitis evolving shortly after administration of a new vaccine against human papilloma virus (HPV) recently approved for the prevention of diseases caused by HPV types 6, 11, 16, and 18.
Opsoclonusmyoclonus after human papilloma virus vaccine in a pediatric patientq
Parkinsonism and Related Disorders
journal homepage: www.elsevier.com/locate/parkreldis
Letter to the Editor
1. Introduction
Opsoclonus-Myoclonus Syndrome (OMS) is a rare neurologic
condition comprised of the two hallmark signs of dysmetric ocular
ataxia and myoclonic jerks of the extremities. The eye movements
have been described as ‘‘dancing eyes’’. The eyes dart involuntarily
away from the point of visual fixation or pursuit in a manner that
can be considered a myoclonic jerk of the extra-ocular muscles.
When the patient attempts to align the gaze on a point, there may
be dysmetric overshoot of the eyemovement.Myoclonicmovements
of the extremities occur at rest, and intended actions are ataxic. The
mean age of presentation of OMS in childhood is 14 months, and it
presents as a paraneoplastic syndromeassociated with an underlying
tumor in 50–60% of the cases [1,2], most commonly neuroblastoma
or ganglioneuroblastoma. Recent research has revealed the presence
of several auto-antibodies including anti-Hu, anti-Ri, a-Enolase,
KSRP and NLK [3] in patients with OMS. These antibodies bind to
an array of targets in the cerebellum andmaymanifest as oligoclonal
bands in cerebrospinal fluid. The syndrome is often associated
with behavioral changes such as aggression, irritability, and
insomnia. Post-vaccine OMS is not well described in the pediatric
population.
Multiple Evanescent White Dot Syndrome After Vaccination for Human Papilloma Virus and Meningococcus
Journal of Pediatric Ophthalmology & Strabismus • Vol. xx, No. x
Steven M. Cohen, MD
From the University of South Florida School of Medicine, Tampa, Florida.
Originally submitted July 10, 2008. Accepted for publication October 29, 2008.
The author has no financial or proprietary interest in the materials presented herein.
Multiple evanescent white dot syndrome is a rare chorioretinopathy causing transitory vision loss, usually in females and generally in one eye. In 2007, widespread vaccination of older children against human papilloma virus and meningococcus was recommended by the Centers for Disease Control and Prevention. A 17-year-old girl presented with multiple evanescent white dot syndrome 1 month after receiving these two vaccinations. [J PediatrOphthalmol Strabismus 200X;XX:XX-XX.]
Cervical cancer jab researcher warns of risks
Irish Examiner.com
By Jennifer Hough
Monday, August 30, 2010
THE leading researcher in the development of the cervical cancer vaccine, Gardasil, has called it a “public health experiment” and has warned that parents must be made aware of the serious adverse events associated with its use.
The vaccination programme is set to be rolled out here next month, targeting first- and second-year secondary school students.
However, Dr Diane Harper, who carried out safety studies to get Gardasil approved, warned of “serious adverse events including death” associated with it.