Authors: Claire P. Reese, Petra Brhlikova, Allyson M. Pollock Abstract Summary We conducted a critical appraisal of published Phase 2 and 3 efficacy trials in relation to the prevention of cervical cancer in women. Our analysis shows the trials themselves generated significant uncertainties undermining claims of efficacy in these data. There were 12 randomised control […]
Dr. Sin Hang Lee Challenges Medical and Scientific Community
By Norma Erickson In an unprecedented move, pathologist/clinical microbiologist, Dr. Sin Hang Lee has decided to invite the international community of scientists and medical professionals to peer-review and/or discuss his latest research “Toll-like receptor 9 agonist in HPV vaccine Gardasil 9” in an open public forum. According to Dr. Lee, during 2011/12, when he tried […]
Lessons learnt in Japan from adverse reactions to the HPV vaccine: a medical ethics perspective
Authors: Hirokuni Beppu, Masumi Minaguchi, Kiyoshi Uchide, Kunihiko Kumamoto, Masato Sekiguchi, Yukari Yaju Abstract: The human papillomavirus (HPV) vaccine has been linked to a number of serious adverse reactions. The range of symptoms is diverse and they develop in a multi-layered manner over an extended period of time. The argument for the safety and effectiveness of […]
The impact of HPV vaccination on future cervical screening: a simulation study of two birth cohorts in Denmark
Authors: Mie Sara Hestbech, Elsebeth Lynge, Jakob Kragstrup, Volkert Siersma, Miguel Vazquez-Prada Baillet, John Broderson Abstract: Objectives To explore the interplay between primary and secondary prevention of cervical cancer by estimating future screening outcomes in women offered human papillomavirus (HPV) vaccination when they were sexually naïve. Design Estimation of outcome of liquid-based cytology screening for a post-HPV vaccination […]
Quadrivalent Human Papillomavirus Vaccine and the Young Ovary: Review of Safety Research Following Two Case Series of Premature Ovarian Insufficiency
Author: Dr. D. Little Abstract: The quadrivalent virus-like particle vaccine against human papillomavirus (QHPV) is a population vaccine targeting peri-pubertal girls and boys. Focus on evaluation of adolescent ovarian safety arises from cases in primary care and published case series describing the development of menstrual dysfunction and idiopathic premature ovarian insufficiency (POI) following QHPV vaccination. […]
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