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HPV: Non-sexual means of transmission

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Non sexual means Abstract Aim: There is strong evidence to suggest vertical and horizontal modes of transmission of human papilloma virus (HPV), an established etiologic agent of cervical cancer. Infants, children, and adults can acquire both high-risk and low-risk infections by birth or by close contact even though HPV is mainly transmitted sexually. A thorough […]

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Transvaginal ultrasound probe contamination by the human papillomavirus in the emergency department.

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Is 'protecting' against 4 types of HPV enough to warrant the risks?

Transvaginal contamination Ma ST, et al. Emerg Med J. 2013. Abstract OBJECTIVE: To determine if human papillomavirus (HPV) DNA can be detected on the transvaginal sonography (TVS) probe in the emergency department (ED) and whether the current barrier method plus disinfection can prevent HPV contamination of the TVS probe. METHODS: This was a two-part cross-sectional […]

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Prevalence of type-specific HPV among female university students from northern Brazil

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Authors: Rodrigo Covre Vieira1*, Jeniffer do Socorro Valente Monteiro2, Estéfane Primo Manso2, Maria Renata Mendonça dos Santos3, Mihoko Yamamoto Tsutsumi4, Edna Aoba Yassui Ishikawa1, Stephen Francis Ferrari5,Karla Valéria Batista Lima6 and Maísa Silva de Sousa1 Abstract Background Human papillomavirus (HPV) infection is associated with cervical cancer, the most frequent cancer in women from northern Brazil. Assessment […]

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Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind

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Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind Authors: S Y Chan, L Ho, C K Ong, V Chow, B Drescher, M Dürst, J ter Meulen, L Villa, J Luande, H N Mgaya Abstract We have amplified by the polymerase chain reaction, […]

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Transmission of High-Risk Human Papillomavirus (HPV) between Parents and Infant: a Prospective Study of HPV in Families in Finland

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Transmission of HPV Authors:  Marjut A. M. Rintala1,* Seija E Grénman1, Mirja H. Puranen2,3, Erika Isolauri4, Ulla Ekblad1, Pentti O. Kero4 and Stina M. Syrjänen2,3 ABSTRACT The Finnish HPV Family Study is a prospective cohort study assessing the dynamics of human papillomavirus (HPV) transmission between parents and infant. Serial genital and oral scrapings from 76 families, including mother, father, and infant, and […]

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Human papillomavirus (HPV) is not the main cause of preinvasive and invasive cervical cancer among patients in Delta Region, Egypt

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Is 'protecting' against 4 types of HPV enough to warrant the risks?

Human papillomavirus (HPV) is not the main cause of preinvasive and invasive cervical cancer among patients in Delta Region, Egypt Authors: Thabet M, Hemida R, Hasan M, Elshamy M, Elfaraash M, Emam M. Abstract BACKGROUND: Cervical cancer remains a significant problem worldwide particularly in underdeveloped countries. It is necessary to have a persistent infection of the […]

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Human Papillomavirus in Infants: Transmission, HPV Prevalence, and Persistence

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Is 'protecting' against 4 types of HPV enough to warrant the risks?

HPV Prevalence, and Persistence Author: Delese E. LaCour, MD* Introduction HPV prevalence. Infections caused by human papillomavirus (HPV) result in considerable morbidity and mortality throughout the world.1–4 Conditions such as anogenital warts, caused by low-risk HPV genotypes and cervical dysplasia, more commonly caused by oncogenic HPV types, can affect females in all age groups.5–9 The prevalence […]

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HPV prevalence and pre-cancer and cancer risk in regular immigrants in Italy: results from HPV DNA test-based screening pilot programs

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Cancer Risk Authors: Cinzia Campari12, Chiara Fedato3, Alessio Petrelli4, Manuel Zorzi5, Carla Cogo5, Adele Caprioglio6, Federica Gallo6, Livia Giordano6, Serena Domenighini7, Luigi Pasquale7, Sonia Prandi8, Marco Zappa9, Paolo Giorgi Rossi102* and the GISCi Migrant Working Group Abstractᅟ Immigrants from low- and medium-income countries have a higher risk of cervical cancer due both to barriers in access […]

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HPV genotype distribution in cervical, vulvar and vaginal disease

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Is 'protecting' against 4 types of HPV enough to warrant the risks?

Global availability of data on HPV genotype distribution in cervical, vulvar and vaginal disease and genotype specific prevalence and incidence of HPV infection in females Authors: Monika Wagner1*, Liga Bennetts1, Harshila Patel1, Sharon Welner1, Silvia de Sanjose34 andThomas W Weiss2 Abstract (provisional) Background Country-level HPV genotyping data may be sought by decision-makers to gauge the genotype […]

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Cytokine levels in cervical cancers: HPV 16-18 vs non HPV 16-18 genotypes

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IL-10, IL-15, IL-17, and GMCSF levels in cervical cancer tissue of Tanzanian women infected with HPV16-18 vs. non-HPV16-18 genotypes By Adriana C Vidal1, David Skaar2, Rachel Maguire2, Seyram Dodor3, Laura W Musselwhite4, John A Bartlett5, Olola Oneko6, Joseph Obure6, Pendo Mlay6, Susan K Murphy7 and Cathrine Hoyo2* Abstract Background Despite comparable screening rates for precancerous lesions, […]

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From Human Papillomavirus (HPV) Detection to Cervical Cancer Prevention in Clinical Practice

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Cervical Cancer Prevention Sin Hang Lee, Jessica S. Vigliotti, Veronica S. Vigliotti and William Jones Abstract: The newly gained knowledge of the viral etiology in cervical carcinogenesis has prompted industrial interests in developing virology-based tools for cervical cancer prevention. Due to the long incubation period from viral infection to developing an invasive cancer, a process whose […]

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High prevalence of hpv multiple genotypes in women with persistent chlamydia trachomatis infection

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Silva Seraceni1†, Francesco De Seta12, Claudia Colli3, Rossella Del Savio1, Giuliano Pesel1, Valentina Zanin1, Pierlanfranco D’Agaro12,Carlo Contini4 and Manola Comar12*† Abstract Background Chlamydia trachomatis interaction with HR-HPV types has highlighted a central role in cervical cancer development. The aim of this study was to investigate HPV prevalence and genotypes distribution in women at risk for […]

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Co-infection with HPV types from the same species provides natural cross-protection from progression to cervical cancer

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Co-infection with HPV types from the same species provides natural cross-protection from progression to cervical cancer Rafal S Sobota126*, Doreen Ramogola-Masire345, Scott M Williams2 andNicola M Zetola345* Abstract Background The worldwide administration of bivalent and quadrivalent HPV vaccines has resulted in cross-protection against non-vaccine HPV types. Infection with multiple HPV types may offer similar cross-protection […]

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Human papillomavirus genotypes in cervical cancer and vaccination challenges in Zimbabwe

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Human papillomavirus genotypes in cervical cancer and vaccination challenges in Zimbabwe HPV Genotypes: Nyasha Chin’ombe1*, Natasha L Sebata1, Vurayai Ruhanya1 and Hilda T Matarira2 Abstract Cervical cancer is one of the major causes of morbidity and mortality in women in Zimbabwe. This is mainly due to the high prevalence of high-risk human papillomavirus (HPV) genotypes in the population. So […]

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Potential cross reactivity between HPV 16 L1 protein and sudden death-associated antigens

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Potential cross reactivity Cross Reactivity… J Exp Ther Oncol. 2011;9(2):159-65. Kanduc D. Author information Abstract In exploring the primary sequence of the human papilloma virus (HPV) 16 major capsid L1 protein for peptide sharing with human proteins, we find that 34 pentamers from the viral capsid protein are shared with human proteins that, when altered, have […]

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Prevalence and type distribution of high-risk human papillomavirus in patients with cervical cancer: a population-based study

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Prevalence Mohammadreza Haghshenas1, Tahereh Golini-moghaddam2, Alireza Rafiei1, Omid Emadeian2, Ahmad Shykhpour1 and G Hossein Ashrafi3* Abstract Background Cervical cancer is the greater cause of cancer death in women in many developing countries. Persistent infection with human papilloma virus (HPV), primarily high risk types 16 and 18, is recognized as a causal and essential factor for the development of cervical cancer. We […]

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HPV prevalence and genetic predisposition to cervical cancer in Saudi Arabia

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Genetic Predisposition Corresponding author: Ghazi Alsbeih galsbeih@kfshrc.edu.sa Background Cervical cancer incidence is low in Saudi Arabian women, suggesting low prevalence to HPV infection due to environmental, cultural and genetic differences. Therefore, we investigated HPV prevalence and genotype distribution in cervical cancer as well as the association with 9 genetic single nucleotide polymorphisms (SNPs): CDKN1A (p21) C31A, TP53 C72G, ATM G1853A, HDM2promoter T309G, HDM2 A110G, LIG4 A591G, XRCC1 G399A, XRCC3 C241T and TGFβ1 T10C, […]

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Topological conformational changes of human papillomavirus (HPV) DNA bound to an insoluble aluminum salt—A study by low temperature PCR

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Gardasil Cervarix HPV Vaccine Survey

Author(s):  Sin Hang Lee ABSTRACT A low temperature (LoTemp®) polymerase chain reaction (PCR), conducted at cycling temperatures not to exceed 85℃and catalyzed by a novel highly processive HiFi® DNA polymerase with proofreading function, was used to study the topological conformational changes of the human papillomavirus (HPV) L1 gene DNA fragments bound to the insoluble amorphous aluminum […]

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Death after Quadrivalent Human Papillomavirus (HPV) Vaccine: Causal or Coincidental?

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Lucija Tomljenovic1* and Christopher A Shaw1,2,3 1Department of Ophthalmology and Visual Sciences, University of British Columbia, Canada 2Program in Experimental Medicine, University of British Columbia, Canada 3Program in Neuroscience, University of British Columbia, Canada Abstract: Background: The proper understanding of a true risk from vaccines is crucial for avoiding unnecessary adverse  reactions (ADRs). However, to […]

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Human papillomavirus genotype distribution among French women with and without cervical abnormalities.

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Int J Gynaecol Obstet. 2011 Aug;114(2):116-9. Epub 2011 Jun 12. Casalegno JS, Benchaib M, Le Bail Carval K, Piaton E, Mathevet P, Mekki Y. Source: Laboratory of Virology, Femme-Mère-Enfant Hospital, Bron, France.   Abstract OBJECTIVE: To assess human papillomavirus (HPV) prevalence and distribution among French women with normal and pathologic cytology findings. METHODS: A genomic DNA microarray assay enabling the detection […]

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