November 2, 2010 The Honorable Margaret Hamburg, M.D., Commissioner, FDA The Honorable Harold E. Varmus, M.D., Director,NCI Subject: Request recommending a reliable human papillomavirus (HPV) genotyping test to support the national virology-based cervical cancer prevention program for patient care Dear Dr. Hamburg and Dr. Varmus: A recently published letter to the editor of ‘Obstetrics and […]
What Your Doctor May Not Tell You After an HPV Diagnosis: An Editorial
By Bonnie Diraimondo, RN For many women, a diagnosis of HPV may come in the mail via a form letter. Some doctor’s offices will contact the patients by telephone and inform them that they test positive for HPV. But what happens after this? If you happen to be informed at one of your routine visits, […]
Automation of the linear array HPV genotyping test and its application for routine typing of human papillomaviruses in cervical specimens of women without cytological abnormalities in Switzerland.
Dobec M, Bannwart F, Kaeppeli F, Cassinotti P. Medica, Medizinische Laboratorien Dr F Kaeppeli, Zurich, Switzerland. m.dobec@medica-labor.ch Abstract BACKGROUND: There is a need for reliable, automated high throughput HPV detection and genotyping methods for pre- and post-prophylactic vaccine intervention analyses. OBJECTIVES: To optimize the linear array (LA) HPV genotyping test (Roche Diagnostics, Rotkreuz) in regard […]
Signature sequence validation of human papillomavirus type 16 (HPV-16) in clinical specimens.
Lee SH, Vigliotti VS, Pappu S. J Clin Pathol. 2010 Mar;63(3):235-9. Epub 2009 Oct 26. Abstract AIMS: Persistent infection indicated by detection of human papillomavirus 16 (HPV-16) on repeat testing over a period of time poses the greatest cervical cancer risk. However, variants of HPV-16, HPV-31 and HPV-33 may share several short sequence homologies in […]