November 2, 2010 The Honorable Margaret Hamburg, M.D., Commissioner, FDA The Honorable Harold E. Varmus, M.D., Director,NCI Subject: Request recommending a reliable human papillomavirus (HPV) genotyping test to support the national virology-based cervical cancer prevention program for patient care Dear Dr. Hamburg and Dr. Varmus: A recently published letter to the editor of ‘Obstetrics and […]
HPV Genotyping by DNA Sequencing for safe and necessary HPV vaccination now in standard textbook
Molecular Diagnostics: Techniques and Applications for the Clinical Laboratory By Wayne W. Grody, Robert M. Nakamura, Frederick L. Kiechle Page 302 D. HPV Vaccination and HPV Genotyping …In addition, a HPV genotyping assay will help identify women who have, or have had, an abnormal cytology or a high-risk HPV infection detected by HCII, but they […]
Behind the Scenes: The Evolution of an HPV Industry
By Norma Erickson, President of SaneVax Inc. April 5, 2011 The first papillomavirus was discovered in the 1930’s by Dr. Richard E. Shope. It was the cottontail rabbit papillomavirus, or the Shope papillomavirus, which occurred in warts that frequently developed into cancerous tumors1. Dr. Shope was able to isolate the virus, inject it into […]
Automation of the linear array HPV genotyping test and its application for routine typing of human papillomaviruses in cervical specimens of women without cytological abnormalities in Switzerland.
Dobec M, Bannwart F, Kaeppeli F, Cassinotti P. Medica, Medizinische Laboratorien Dr F Kaeppeli, Zurich, Switzerland. m.dobec@medica-labor.ch Abstract BACKGROUND: There is a need for reliable, automated high throughput HPV detection and genotyping methods for pre- and post-prophylactic vaccine intervention analyses. OBJECTIVES: To optimize the linear array (LA) HPV genotyping test (Roche Diagnostics, Rotkreuz) in regard […]
Validation of human papillomavirus genotyping by signature DNA sequence analysis.
Lee SH, Vigliotti VS, Vigliotti JS, Pappu S. BMC Clin Pathol. 2009 May 22;9:3. Department of Pathology, Milford Hospital, Milford, Connecticut, USA. sinhang.lee@milfordhospital.org Abstract BACKGROUND: Screening with combined cytologic and HPV testing has led to the highest number of excessive colposcopic referrals due to high false positive rates of the current HPV testing in the […]
