By John Gever, Senior Editor, MedPage Today
A five-week-old Canadian infant developed yellow fever after his mother was vaccinated against the disease, with the virus apparently transmitted through breast milk, researchers said.
The incident — believed to be the first such transmission to be confirmed — supports what had been a hypothetical concern about live-virus yellow fever vaccination, according to Susan Kuhn, MD, MSc, of the University of Calgary, Alberta, and colleagues.
“Previously, recommendations cautioning against use of the vaccine in lactating women had been justified on theoretical grounds only,” Kuhn and co-authors wrote online in CMAJ, the Canadian Medical Association’s journal. Although the vaccine has been in use for decades, no actual episodes had been documented.