Wingfield T, McHugh C, Vas A, Richardson A, Wilkins E, Bonington A, Varma A. Source The Monsall Unit, Department of Infectious Diseases and Tropical Medicine, North Manchester General Hospital, Manchester, UK. tomwingfield@hotmail.co.uk Abstract Encephalitic syndromes are a common medical emergency. The importance of early diagnosis and appropriate treatment is paramount. If initial investigations for infectious agents prove negative, other diagnoses must […]
Assuring the Quality, Safety, and Efficacy of DNA Vaccines
Robertson JS, Griffiths E Source National Institute for Biological Standards and Control, Herts, UK. Methods Mol Med. 2006;127:363-74. Abstract Scientists in academia whose research is aimed at the development of a novel vaccine or approach to vaccination may not always be fully aware of the regulatory process by which a candidate vaccine becomes a licensed product. It […]
Investigating Viruses in Cells Used to Make Vaccines; and Evaluating the Potential Threat Posed by Transmission of Viruses to Humans
FDA Vaccines Blood & Biologics Principal Investigator: Arifa S. Khan, PhD Office / Division / Lab: OVRR / DVP / LR General Overview The emergence of pathogenic virus infections like influenza and HIV have created an urgent need for new vaccines. Virus-based vaccines are made in living cells (cell substrates). Some manufacturers are investigating the […]
Attitudes toward HPV Vaccination among Women Aged 27 to 45.
Pub Med SRN Obstet Gynecol.2011;2011:670318. Epub 2011 Apr 7. Weiss TW, Rosenthal SL, Zimet GD. Source Global Health Outcomes, Merck & Co., Inc., P.O. Box 4, WP97-A243, 770 Sumneytown Pike, West Point, PA 19486-0004, USA. Abstract The purpose of this study was to identify attitudes toward HPV vaccination among US women 27 to 45 years […]
Estrogens regulate neuroinflammatory genes via estrogen receptors alpha and beta in the frontal cortex of middle-aged female rats
7th Space Interactive July 23, 2011 Estrogens exert anti-inflammatory and neuroprotective effects in the brain mainly via estrogen receptors alpha (ERalpha) and beta (ERbeta). These receptors are members of the nuclear receptor superfamily of ligand-dependent transcription factors. This study was aimed at the elucidation of the effects of ERalpha and ERbeta agonists on the expression […]