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HPV4 not associated with autoimmune conditions

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Infectious Disease News

Posted September 13, 2010

BOSTON — The quadrivalent human papillomavirus vaccine did not raise the risk for developing autoimmune conditions, according to data presented here at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy.

In a study sponsored by Merck and conducted on behalf of the Gardasil Safety Team, researchers investigated the safety of the quadrivalent HPV vaccine (HPV4; Gardasil, Merck). The researchers honed in on identifying 16 prespecified rheumatologic, endocrine and neurologic or ophthalmologic autoimmune conditions.

During the post-licensure, observational study, the researchers monitored girls and women in managed care organizations who received at least one dose of HPV4 between August 2006 and March 2008. Follow-up lasted for 6 months after administration of each dose.

The researchers found 11 conditions among a random sample of girls and women who had at least a 12-month health care plan before HPV4 vaccination. Clinicians reviewed medical records to verify diagnosis and determine time of disease onset. Incidence rates for each condition were also established for vaccinated and unvaccinated participants during case identification and review.

Más mercado (y víctimas) de la vacuna VPH

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Publicado por Miguel Jara el

Spain
13 de Septiembre de 2010

La campaña para expandir la polémica vacunación contra el virus del papiloma humano toma fuerza. Hasta ahora sólo se podía vacunar a las niñas pero la Comisión Europea ha extendido su administración a mujeres de hasta 45 años.

Hay algunas cosas que llaman la atención. La primera de ellas es que antes decían que esta vacuna estaba indicada para las jóvenes que no habían iniciado relaciones sexuales ya que según un estudio realizado con una de las marcas del preparado, Gardasil, del laboratorio Merck, si la joven estaba infectada había un 44,6% de posibilidades de contraer cáncer de útero. Ahora parece que obvian este estudio. Desde la Asociación de Afectadas por la Vacuna contra el Papiloma opinan:

“Creemos que este dato no se puede obviar y todas las mujeres deberían hacerse una citología o pruebas antes de recibir la vacuna para ver si están infectadas, de lo contrario en lugar de prevenir la hipotética posibilidad de contraer cáncer de útero, incrementarían esta posibilidad en un 44,6%“.

MOTHERS ALLIANCE IRELAND CALLS ON THE GOVERNMENT TO STOP THE SCHOOLS’ VACCINATION CAMPAIGN IMMEDIATELY, IN THE BEST INTERESTS OF THE NATION’S CHILDREN.

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SANE Vax.org

September 10, 2010. Mothers Alliance Ireland claims THE SCHOOLS VACCINATION CAMPAIGN, which is to be rolled out this month in Irish Schools for 12/13 year-old girls, poses a serious risk to the lives, health and welfare of Irish children, and it MUST BE ABANDONED IMMEDIATELY.

“Critical information concerning the Gardasil vaccine is being withheld from parents and the public and as a result parents are being denied the right to make a valued and fully informed decision about whether or not to consent to getting their daughters vaccinated”, said Mrs. Nora Bennis, MAI spokesperson. MAI has written to the Minister for Health and Minister for Education outlining the very serious concerns the group has about the safety, efficacy and necessity of this vaccine.

Th1 cytokine patterns in cervical human papillomavirus infection.

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PubMed.gov

Clin Diagn Lab Immunol. 1999 Sep;6(5):751-5.

Scott M, Stites DP, Moscicki AB.

Department of Pediatrics, University of California, San Francisco, California 94143, USA. mscott@itsa.ucsf.edu
Abstract

The host’s immune response to cervical human papillomavirus (HPV) infection is poorly understood. In a longitudinal cohort of women with cervical HPV infections, defined by PCR-based HPV DNA testing, we used exfoliated cervical cells and reverse transcription-PCR to examine the cervical mucosal mRNA expression of cytokines involved in regulating cell-mediated immunity. We identified seven HPV-positive subjects who were found to have cleared their HPV infections 4 months later. In all seven, a T-helper type 1 (Th1) cytokine pattern (expression of gamma interferon and absence of interleukin-4) preceded clearance. The more variable cytokine patterns seen in HPV-negative subjects suggest that the Th1 pattern in the women with subsequent clearance was a response to the HPV infection.

What Really Went Wrong with Gardasil

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SEO Press Releases

North Hollywood, CA, September 10, 2010 — On September 7, 2010, Shelly Dubois wrote an article for Fortune – on CNNMoney.com, titled: What’s Wrong with Gardasil. SANE Vax.org believes that the article discredits the thousands of families, who have suffered deaths and adverse injuries to their daughters in the name of financial numbers and award-winning marketing strategies.

The article opens with: “There’s a liquid drug that women can get injected into a layer of muscle — three separate times over a six-month period — that can protect them from a kind of cancer. From a scientific perspective, that’s amazing. In terms of public health, it’s a breakthrough.

“But four years after Merck (MRK, Fortune 500) released this would-be top-seller, called Gardasil, it has proven to be a marketplace dud. In Merck’s second quarter, the company reported an 18% year-over-year drop in sales to $219 million and its stock is down nearly 3% to date. Analysts are pointing to Gardasil not as a savior, but as a risk for investors.”

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