J. Douglas Bremner, Peter McCaffery Abstract Current models of affective disorders implicate alterations in norepinephrine, serotonin, dopamine, and CRF/cortisol; however treatments targeted at these neurotransmitters or hormones have led to imperfect resolution of symptoms, suggesting that the neurobiology of affectivedisorders is incompletely understood. Until now retinoids have not been considered as possible contributors to affective […]