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You are here: Home / NEWS . . . . . . . . / Vaccines / HPV / More Flexible HPV Vaccines

More Flexible HPV Vaccines

April 15, 2011 By Norma Leave a Comment

(Ivanhoe Newswire) — Administration of human papillomavirus (HPV) vaccine doses over a longer period of time to adolescent girls in Vietnam resulted in antibody concentration levels that were comparable to the standard vaccine schedule, according to a new study.

Cervical cancer is an important cause of illness and death among women throughout the world.

“Each year, new cases of cervical cancer occur in approximately 529,000 women, and 275,000 women die. An estimated 88 percent of deaths due to cervical cancer occur among women residing in developing countries,” according to background information in the article. Human papillomaviruses are the primary cause of cervical cancer.

“Combined with continued strengthening of simple evidence-based screening and treatment approaches, effective HPV vaccine programs could reduce cervical cancer rates in developing countries to the low levels currently observed in many developed countries. One challenge to broadly implementing HPV vaccination programs in developing countries will be delivering the currently recommended three doses of vaccine to adolescents within six months (dosing schedules at zero, two, and six months or at zero, one, and six months),” the authors write.

Kathleen M. Neuzil, M.D., M.P.H., of PATH, Seattle, and colleagues conducted a randomized trial to determine the immunogenicity (the ability of the vaccine to stimulate an immune response) and the reactogenicity (the capacity of a vaccine to produce adverse reactions) of alternative schedules of quadrivalent HPV vaccine. The study assessed four schedules of an HPV vaccine delivered in 21 schools to 903 adolescent girls (ages 11-13 years at enrollment).

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Filed Under: HPV, HPV Science, Vaccine Science Tagged With: extended dosage schedule, immune response

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HPV Vaccine VAERS Reports

Description 12/14/2019  TOTAL
Disabled 3,092
Deaths 523
Did Not Recover 13,072
Abnormal Smear 695
Cervical Cancer 186
Infertility 52
Life-threatening 1,001
Emergency Room 15,419
Hospitalized 6,448
Extended Hosp. Stay 304
Serious 9,497
Total Adverse Events 64,270

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