Ethiopian Review October 2, 20102 What It Is, the Role of HPV, and How It May Be Prevented What Is Cervical Cancer? The cervix forms the opening to the uterus from the vagina. It is covered with two main types of cells: squamous cells, which cover the part of the cervix that extends into the […]
Detection of sexually transmitted infection and human papillomavirus in negative cytology by Multiplex-PCR
7th Space Interactive The aim of this study was to determine the prevalence of human papillomavirus (HPV) and 15 species that cause sexually transmitted infections (STIs) in negative cytology. In addition, we compared the diagnostic performance of multiplex polymerase chain reaction (PCR) with widely available techniques used to detect HPV. Methods: We recruited 235 women […]
An Interview with Dr. Diane Harper
Marcia G. Yerman December 2009 Throughout my examination of the Gardasil vaccine, there has been a steady flow of information, disinformation, and new developments. In my opening article, I wrote about the mandatory ruling in July of 2008 by the U.S. Citizenship and Immigration Services (USCIS) that would require all female green card applicants and […]
Experts call for more cervical cancer tests
Trinidad & Tobago’s Newsday
By LARA PICKFORD GORDON Tuesday, September 7 2010
SEXUALLY active females, even those classified as “children”, should get screened as a precaution against cervical cancer.
According to Professor Kimlin Tam Ashing, Professor, Department of Population Sciences and Director of the Centre of Community Alliance for Research and Education, City of Hope US, screening should start among females 18 years-old. However, she qualified this statement saying it should take place at the time of sexual initiation.
“Unfortunately, that could be 12 or 14 so at that age if the child, she is a child, has begun sexual activity she really needs to be getting a pap test,” she said at the launch of the research study, “Role of Stigma in Cervical Cancer Screening in Trinidad and Tobago” at the Carlton Savannah. Among its aims is to identify the barriers to cervical cancer screening.
Cancer is the second leading cause of death in TT and data from the National Cancer Registry indicated that cervical cancer is the second leading cancer among women. Breast cancer ranks first. The pap smear test can be done annually or more frequently depending on what is found in the cells. Cervical cancer is caused by the human papilloma virus (HPV) which is sexually transmitted and can cause cancerous cellular changes which affect the area at the opening of the uterus.
Prevalence of Human Papillomavirus Types in High-Grade Cervical Intraepithelial Neoplasia and Cancer in Italy
American Association for Cancer Research
Francesca M. Carozzi1, Maria L. Tornesello2, Elena Burroni1, Giovanna Loquercio2, Giuseppe Carillo3, Claudio Angeloni4, Aurora Scalisi5, Rosalba Macis6, Francesco Chini7, Franco M. Buonaguro2, Paolo Giorgi Rossi7 and for the HPV Prevalence Italian Working Group
Corresponding Author:
Paolo Giorgi Rossi, Laziosanità, Via di Santa Costanza, 53, Rome 00198, Italy. E-mail: giorgirossi@asplazio.it
Abstract
Background: The aim of this multicentric study was to identify human papillomavirus (HPV) type distribution in invasive cervical cancer and high-grade cervical intraepithelial neoplasia 2/3 (CIN2/3) in Italy.
Methods: Cases were sampled through the electronic databases at the pathology units of eight centers in six regions from central and southern Italy. HPV types were detected from paraffin-embedded tissue samples and cervical specimens through amplification of HPV DNA with GP5+/GP6+ primers, followed by genotyping with reverse line blot (RLB). Untyped HPV-positive samples were sequenced. HPV-negative samples underwent nested PCR, followed by either RLB or sequencing. Finally, the remaining HPV-negative samples were amplified with primers targeting the virus E6 to E7 regions.