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You are here: Home / NEWS . . . . . . . . / World News / South America / Brazil / Prevalence of type-specific HPV among female university students from northern Brazil

Prevalence of type-specific HPV among female university students from northern Brazil

August 19, 2015 By Norma

Authors: Rodrigo Covre Vieira1*, Jeniffer do Socorro Valente Monteiro2, Estéfane Primo Manso2, Maria Renata Mendonça dos Santos3, Mihoko Yamamoto Tsutsumi4, Edna Aoba Yassui Ishikawa1, Stephen Francis Ferrari5,Karla Valéria Batista Lima6 and Maísa Silva de Sousa1

Abstract

Background

Human papillomavirus (HPV) infection is associated with cervical cancer, the most frequent cancer in women from northern Brazil. Assessment of the short-term impact of HPV vaccination depends on the availability of data on the prevalence of type-specific HPV in young women in the pre-immunization period, although these data are currently unavailable for the study region. The aim of this study was to estimate the distribution of all mucosal HPV genotypes, including low- and high-risk HPV types, in unvaccinated college students from northern Brazil.

Findings

Specimens were collected from 265 university students during routine cervical cancer screening. The HPV DNA was assessed by Polymerase Chain Reaction and positive samples were genotyped by Restriction Fragment Length Polymorphism. Most students (85.7 %) had normal cytological results. The prevalence of HPV was 25.3 % (67/265), with a high frequency of multiple infections and non-vaccine high-risk HPV genotypes. The most prevalent type was HPV-61 (5.3 %), followed by types 82, 16, 59, and 6. Multiple infections were associated with high-risk and possibly high-risk HPVs.

Conclusions

We demonstrated a high prevalence of HPV infection in university students from northern Brazil. Vaccine high-risk types were relatively rare, emphasizing the predominance of carcinogenic genotypes that are not prevented by the currently available vaccines. Our study highlights the need to reinforce cytological screening in women from northern Brazil, and promote the early diagnosis and treatment of the precancerous lesions associated with cervical cancer.

Read the entire paper here.

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Filed Under: Brazil, Human Papillomavirus Research Tagged With: genotype distribution, HPV vaccine impact, human papillomavirus, prevalence

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HPV Vaccine VAERS Reports

Description 12/14/2019  TOTAL
Disabled 3,092
Deaths 523
Did Not Recover 13,072
Abnormal Smear 695
Cervical Cancer 186
Infertility 52
Life-threatening 1,001
Emergency Room 15,419
Hospitalized 6,448
Extended Hosp. Stay 304
Serious 9,497
Total Adverse Events 64,270

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