Michael J. Conway, Linda Cruz, Samina Alam, Neil David Christensen, Craig Meyers Background: Human papillomavirus (HPV) capsids are composed of 72 pentamers of the major capsid protein L1, and an unknown number of L2 minor capsid proteins. An N-terminal “external loop” of L2 contains cross-neutralizing epitopes, and native HPV16 virions extracted from 20-day-old organotypic tissues […]
Validation of human papillomavirus genotyping by signature DNA sequence analysis.
Lee SH, Vigliotti VS, Vigliotti JS, Pappu S. BMC Clin Pathol. 2009 May 22;9:3. Department of Pathology, Milford Hospital, Milford, Connecticut, USA. sinhang.lee@milfordhospital.org Abstract BACKGROUND: Screening with combined cytologic and HPV testing has led to the highest number of excessive colposcopic referrals due to high false positive rates of the current HPV testing in the […]
Routine human papillomavirus genotyping by DNA sequencing in community hospital laboratories.
Lee SH, Vigliotti VS, Vigliotti JS, Pappu S. Infect Agent Cancer. 2007 Jun 5;2:11. Department of Pathology, Milford Hospital, Milford, Connecticut, USA. sinhang.lee@milfordhospital.org Abstract BACKGROUND: Human papillomavirus (HPV) genotyping is important for following up patients with persistent HPV infection and for evaluation of prevention strategy for the individual patients to be immunized with type-specific HPV […]
HPV infection among women in a representative rural and suburban population of the USA.
Lee SH, Vigliotti VS, Pappu S. Int J Gynaecol Obstet. 2009 Jun;105(3):210-4. Epub 2009 Feb 28. Department of Pathology, Milford Hospital, Milford, Connecticut 06460, USA. sinhang.lee@milfordhospital.org Abstract OBJECTIVE: To study the prevalence of low-risk and high-risk HPV genotypes in a largely suburban, non-Hispanic, white female population of the USA, and to determine the positive […]
Molecular tests for human papillomavirus (HPV), Chlamydia trachomatis and Neisseria gonorrhoeae in liquid-based cytology specimen.
Lee SH, Vigliotti VS, Pappu S. BMC Womens Health. 2009 Apr 9;9:8. Department of Pathology, Milford Hospital, Milford, Connecticut, USA. sinhang.lee@milfordhospital.org Abstract BACKGROUND: Laboratory detection of Human papillomavirus (HPV), Chlamydia trachomatis and Neisseria gonorrhoeae in liquid-based cervicovaginal cytology specimens is now based on identification of the DNA sequences unique to these infectious agents. However, current […]
