The Lancet, Volume 374, Issue 9686, Pages 301 – 314, 25 July 2009 Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections, and associated precancerous lesions in an event-triggered interim analysis of the phase III randomised, double-blind, controlled PApilloma TRIal against Cancer In young Adults […]
Prophylactic HPV Vaccines: Current Knowledge of Impact on Gynecological Premalignancies
Authors: Diane M. Harper/Karen B. Williams Published 3 July 2010, Discovery Medicine Abstract: Approaches for cervical cancer prevention are changing. Screening still remains the most effective method for cervical cancer prevention. Guidelines are moving to an older group of women to be screened less frequently with combinations of technologies that include biomarkers and cytology. HPV […]
Human Papillomavirus (HPV) Vaccine Efficacy Trial Against Cervical Pre-cancer in Young Adults With GlaxoSmithKline (GSK) Biologicals HPV-16/18
Completed 29 June 2010 Purpose: Human Papilloma virus (HPV) are viruses that cause a common infection of the skin and genitals in men and women. Several types of HPV infection are transmitted by sexual activity and, in women, can infect the cervix (part of the uterus or womb). This infection often goes away by itself, […]
HPV Vaccine: Debate Over Benefits, Marketing, and New Adverse Event Data
By: Zosia Chustecka August 18, 2009 — The benefit of vaccinating against human papilloma virus (HPV) to prevent cervical cancer is questioned in an editorial in the Journal of the American Medical Association. “The theory behind the vaccine is sound: if HPV infection can be prevented, cancer will not occur,” writes editorialist Charlotte Haug, MD, […]
Risk of miscarriage with bivalent vaccine against human papillomavirus (HPV) types 16 and 18
Sholom Wacholder, study statistician and principal investigator1, Bingshu Eric Chen, assistant professor2, Allen Wilcox, senior investigator3, George Macones, professor of obstetrics and gynaecology4, Paula Gonzalez, study co-investigator5, Brian Befano, senior programmer6, Allan Hildesheim, study investigator, principal investigator1, Ana Cecilia Rodríguez, study co-investigator5, Diane Solomon, study co-investigator7, Rolando Herrero, study principal investigator5, Mark Schiffman, study co-investigator, […]
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