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Will HPV vaccination prevent cervical cancer?

January 22, 2020 By Norma

Authors: Claire P. Reese, Petra Brhlikova, Allyson M. Pollock Abstract Summary We conducted a critical appraisal of published Phase 2 and 3 efficacy trials in relation to the prevention of cervical cancer in women. Our analysis shows the trials themselves generated significant uncertainties undermining claims of efficacy in these data. There were 12 randomised control […]

Filed Under: Gardasil/Silgard Clinical Trials, Gardasil/Silgard Efficacy Tagged With: clinical trials, HPV vaccine efficacy

Do cervical cancer data justify HPV vaccination in India? Epidemiological data sources and comprehensiveness

June 24, 2012 By Norma Leave a Comment

Published in the Journal of the Royal Society of Medicine; June 2012 105:229 Authors: I Mattheij,1   AM Pollock,2 P Brhlikova3 Summary The Indian government suspended research in April 2010 on the feasibility and safety of human papillomavirus (HPV) vaccine in two Indian states (Andhra Pradesh and Gujarat) amid public concerns about its safety. This paper describes cervical cancer […]

Filed Under: Cervarix Clinical Trials, Gardasil/Silgard Clinical Trials, Immunization Practices Tagged With: clinical trials, human papillomavirus vaccine, India, PATH

Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women

January 16, 2011 By Norma

The Lancet, Volume 374, Issue 9686, Pages 301 – 314, 25 July 2009 Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections, and associated precancerous lesions in an event-triggered interim analysis of the phase III randomised, double-blind, controlled PApilloma TRIal against Cancer In young Adults […]

Filed Under: Cervarix, Cervarix Clinical Trials, Gardasil / Silgard Injuries, Gardasil/Silgard Clinical Trials, Gardasil/Silgard Vaccine Tagged With: cervical cancer vaccine, clinical trials, HPV vaccine

HPV DNA testing over 50 percent more sensitive than cytology testing

January 16, 2011 By Norma

Science Centric | 9 July 2010 10:46 GMT HPV DNA testing for precancers and cervical cancers is over 50 per cent more sensitive than cytology testing for the same conditions a community-based study in Mexico has revealed. Results of the largest HPV DNA primary screening study ever to be performed in a Latin American country […]

Filed Under: Gardasil / Silgard Injuries, Gardasil/Silgard Clinical Trials, Gardasil/Silgard Vaccine Tagged With: cervical precancer, colposcopy, HPV DNA testing

Effect of Human Papillomavirus 16/18 L1 Viruslike Particle Vaccine Among Young Women With Preexisting Infection

January 15, 2011 By Norma

A Randomized Trial JAMA. 2007;298:743-753. Main Outcome Measures  Presence of HPV DNA was determined in cervical specimins by a molecular hybridization assay using chemiluminescence with HPV RNA probes and by polymerase chain reaction using SPF10 primers and a line probe assay detection system before vaccination and by polymerase chain reaction after vaccination. We compared rates of […]

Filed Under: Gardasil / Silgard Injuries, Gardasil/Silgard Clinical Trials, Gardasil/Silgard Efficacy Tagged With: HPV DNA, HPV vaccine, vaccination

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This Week’s Survivor

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HPV Vaccine VAERS Reports

Description 12/14/2019  TOTAL
Disabled 3,092
Deaths 523
Did Not Recover 13,072
Abnormal Smear 695
Cervical Cancer 186
Infertility 52
Life-threatening 1,001
Emergency Room 15,419
Hospitalized 6,448
Extended Hosp. Stay 304
Serious 9,497
Total Adverse Events 64,270

Access expanded report here.

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