Authors: Rebecca E. Chandler, Kristina Juhlin, Jonas Fransson, Ola Caster, I. Ralph Edwards, G. Niklas Norén Abstract: Introduction A number of safety signals—complex regional pain syndrome (CRPS), postural orthostatic tachycardia syndrome (POTS), and chronic fatigue syndrome (CFS)—have emerged with human papillomavirus (HPV) vaccines, which share a similar pattern of symptomatology. Previous signal evaluations and epidemiological studies have largely relied on traditional methodologies and signals have been […]