Skip Navigation Links
American Journal of Therapeutics:
January/February 2010 – Volume 17 – Issue 1 – pp 86-91
doi: 10.1097/MJT.0b013e3181a2b1bb
Therapeutic Review
Mosnaim, Aron D PharmD, PhD; Abiola, Rasheed BS; Wolf, Marion E MD; Perlmuter, Lawrence C PhD
Orthostatic hypotension (OH) is regarded as a decrease primarily in systolic blood pressure on changing position from supine to erect. Based on clinical criteria, it is characterized by a decrease in systolic pressure of 20 mmHg and diastolic pressure of 10 mmHg within 1 to 3 minutes of standing after being supine. It is most prevalent in, although not limited to, the elderly population and is characterized by a variety of problems, including diminished cognition and disturbed emotion along with gate problems, falls, and brain and cardiovascular difficulties.