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You are here: Home / RESEARCH . . . . / Vaccine Injuries / Autoimmune Disorders / Postural tachycardia syndrome following human papillomavirus vaccination

Postural tachycardia syndrome following human papillomavirus vaccination

March 31, 2014 By Norma Leave a Comment

Postural tachycardia syndrome

Postural tachycardia syndrome… Blitshteyn S.

Author information

 

Abstract

BACKGROUND AND PURPOSE:

Postural tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system that may have an autoimmune etiology.

METHODS:

Six patients who developed new onset POTS 6 days to 2 months following human papillomavirus vaccination are reported.

RESULTS:

Three patients also had neurocardiogenic syncope, and three patients were diagnosed with possible small fiber neuropathy. Symptoms in all patients improved over 3 years with pharmacotherapy and non-pharmacological measures but residual symptoms persisted. Molecular mimicry with formation of cross-reacting autoantibodies to the potential targets of the autonomic ganglia, neurons, cardiac proteins or vascular receptors is considered as a possible pathogenesis of new onset POTS after immunization.

CONCLUSION:

Correct diagnosis of POTS and awareness that POTS may occur after vaccination in young women is essential for prompt and effective management of this condition.

© 2013 The Author(s) European Journal of Neurology © 2013 EFNS.

Access full article here.

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Filed Under: Autoimmune Disorders, Gardasil/Silgard Reactions Tagged With: HPV vaccination, POTS

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Description 12/14/2019  TOTAL
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