Author: Dr. D. Little Abstract: The quadrivalent virus-like particle vaccine against human papillomavirus (QHPV) is a population vaccine targeting peri-pubertal girls and boys. Focus on evaluation of adolescent ovarian safety arises from cases in primary care and published case series describing the development of menstrual dysfunction and idiopathic premature ovarian insufficiency (POI) following QHPV vaccination. […]
Predicting post-vaccination autoimmunity: Who might be at risk?
Authors: Alessandra Soriano, Gideon Nesher, Yehuda Shoenfeld Abstract Vaccinations have been used as an essential tool in the fight against infectious diseases and succeeded in improving public health. However, adverse effects, including autoimmune conditions may occur following vaccinations (autoimmune/inflammatory syndrome induced by adjuvants – ASIA syndrome). It has been postulated that autoimmunity could be triggered or enhanced by […]
Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature
Somatoform and Sysautonomic Syndromes Authors: Beniamino Palmieri; Dimitri Poddighe; Maria Vadalà; Carmen Laurino; Carla Carnovale; Emilio Clementi Abstract: Human papilloma virus (HPV) is recognized as a major cause for cervical cancer among women worldwide. Two HPV vaccines are currently available: Gardasil® and Cervarix®. Both vaccines enclose viral antigenic proteins, but differ as to the biological systems of culture and the adjuvant components. Recently, a collection […]
Quadrivalent human papillomavirus vaccine and autoimmune adverse events: a case–control assessment of the vaccine adverse event reporting system (VAERS) database
Quadrivalent human papillomavirus vaccine and autoimmune adverse events: a case–control assessment of the vaccine adverse event reporting system (VAERS) database Authors: David A. Geier, Mark R. Geier Abstract: Gardasil is a quadrivalent human papillomavirus (HPV4) vaccine that was approved for use by the US Food and Drug Administration in June 2006. HPV4 vaccine is routinely recommended […]
Postural Orthostatic Tachycardia Syndrome (POTS) – A novel member of the autoimmune family
Postural Orthostatic Tachycardia Syndrome (POTS) Authors: S Dahan, L Tomljenovic, Y Shoenfeld Abstract Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within 10 min of standing or head-up […]
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