Monitoring Impact of a National HPV Vaccination Program in Japan (MINT Study): Rationale, Design and Methods Koji Matsumoto1,*, Nobuo Yaegashi2, Takashi Iwata3, Kazuya Ariyoshi4, Kiyoshi Fujiwara5, Yuko Shiroyama6, Tomoka Usami7, Yoshiaki Kawano8, Koji Horie9, Kouichiro Kawano10, Kiichiro Noda11 and Hiroyuki Yoshikawa1 for MINT Study Group Abstract We have developed a collaborative hospital-based approach to monitoring the impact of a human papillomavirus vaccine on cervical cancer, its precursor lesions […]
Too Fast or Not Too Fast: The FDA’s Approval of Merck’s HPV Vaccine Gardasil
Tomljenovic L, Shaw CA. Early career postdoctoral fellow in the Neural Dynamics Research Group at the University of British Columbia. Professor in the Department of Ophthalmology and Visual Sciences at the University of British Columbia and holds cross appointments with the Program in Experimental Medicine and the Graduate Program in Neuroscience. Abstract There are not many […]
Effect of the human papillomavirus (HPV) quadrivalent vaccine in a subgroup of women with cervical and vulvar disease: retrospective pooled analysis of trial data
Abstract Objectives To determine the effect of human papillomavirus (HPV) quadrivalent vaccine on the risk of developing subsequent disease after an excisional procedure for cervical intraepithelial neoplasia or diagnosis of genital warts, vulvar intraepithelial neoplasia, or vaginal intraepithelial neoplasia. Design Retrospective analysis of data from two international, double blind, placebo controlled, randomised efficacy trials of quadrivalent HPV […]
Approaches to monitoring biological outcomes for HPV vaccination: challenges of early adopter countries
Wong CA, Saraiya M, Hariri S, Eckert L, Howlett RI, Markowitz LE, Brotherton JM, Sinka K, Martinez-Montañez OG, Kjaer SK, Dunne EF. Source: Division of Cancer Prevention and Control, Centers for Disease Control and Prevention, Atlanta, GA, USA. Abstract In this review, we describe plans to monitor the impact of human papillomavirus (HPV) vaccine on […]
CASP8 promoter polymorphism is associated with high-risk HPV types and abnormal cytology but not with cervical cancer
Chatterjee K, Williamson AL, Hoffman M, Dandara C. Division of Medical Virology and Institute of Infectious Disease and Molecular Medicine (IIDMM), University of Cape Town, Cape Town, Republic of South Africa. Abstract Only a small fraction of women infected with human papillomavirus (HPV) progress to cervical cancer pointing to additional risk factors including host genetics […]