Julia M.L. Brotherton MD MPH, Mike S. Gold MD, Andrew S. Kemp MD PhD, Peter B. McIntyre MD PhD, Margaret A. Burgess MD, Sue Campbell-Lloyd RN, on behalf of the New South Wales Health HPV Adverse Events Panel Background: In 2007, Australia implemented the National human papillomavirus (HPV) Vaccination Program, which provides quadrivalent HPV vaccine […]
SANE Vax, Inc. Declares Major Victory in Gardasil Awareness Campaign
Merck Loses 4th Bid to Expand Gardasil® to Older Women PR Log April 8, 2011 by Leslie Carol Botha FOR IMMEDIATE RELEASE In a long awaited decision1 the US FDA has ruled against Merck’s supplemental biologics application license (sBLA) for an indication to use Gardasil [Human Papillomavirus Quadrivalent (Types 6, 11, 16 and 18) Vaccine Recombinant] […]
CASP8 promoter polymorphism is associated with high-risk HPV types and abnormal cytology but not with cervical cancer
Chatterjee K, Williamson AL, Hoffman M, Dandara C. Division of Medical Virology and Institute of Infectious Disease and Molecular Medicine (IIDMM), University of Cape Town, Cape Town, Republic of South Africa. Abstract Only a small fraction of women infected with human papillomavirus (HPV) progress to cervical cancer pointing to additional risk factors including host genetics […]
Efficacy of Quadrivalent HPV Vaccine against HPV Infection
Anna R. Giuliano, Ph.D., Joel M. Palefsky, M.D., Stephen Goldstone, M.D., Edson D. Moreira, Jr., M.D., Mary E. Penny, M.D., Carlos Aranda, M.D., Eftyhia Vardas, M.D., Harald Moi, M.D., Heiko Jessen, M.D., Richard Hillman, M.D., Yen-Hwa Chang, M.D., Daron Ferris, M.D., Danielle Rouleau, M.D., Janine Bryan, Ph.D., J. Brooke Marshall, Ph.D., Scott Vuocolo, Ph.D., Eliav […]
Effect of Human Papillomavirus 16/18 L1 Viruslike Particle Vaccine Among Young Women With Preexisting Infection A Randomized Trial
JAMA. 2007;298:743-753. Main Outcome Measures Presence of HPV DNA was determinedin cervical specimins by a molecular hybridization assay usingchemiluminescence with HPV RNA probes and by polymerase chainreaction using SPF10 primers and a line probe assay detectionsystem before vaccination and by polymerase chain reaction aftervaccination. We compared rates of type-specific viral clearanceusing generalized estimating equations methods at […]
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