Article Date: 07 Jul 2009 – 0:00 PDT The findings of the PATRICIA study are reported in an article Online First and in a future edition of The Lancet. It shows that the HPV-16/18 AS04-adjuvanted vaccine (GlaxoSmithKline) has high efficacy against the precancerous cervical lesions that can eventually lead to cervical cancer. There is confirmation […]
Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final analysis of a double-blind, randomised study in young women
The Lancet, Volume 374, Issue 9686, Pages 301 – 314, 25 July 2009 Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections, and associated precancerous lesions in an event-triggered interim analysis of the phase III randomised, double-blind, controlled PApilloma TRIal against Cancer In young Adults […]
Prophylactic HPV Vaccines: Current Knowledge of Impact on Gynecological Premalignancies
Authors: Diane M. Harper/Karen B. Williams Published 3 July 2010, Discovery Medicine Abstract: Approaches for cervical cancer prevention are changing. Screening still remains the most effective method for cervical cancer prevention. Guidelines are moving to an older group of women to be screened less frequently with combinations of technologies that include biomarkers and cytology. HPV […]
HPV Vaccine: Debate Over Benefits, Marketing, and New Adverse Event Data
By: Zosia Chustecka August 18, 2009 — The benefit of vaccinating against human papilloma virus (HPV) to prevent cervical cancer is questioned in an editorial in the Journal of the American Medical Association. “The theory behind the vaccine is sound: if HPV infection can be prevented, cancer will not occur,” writes editorialist Charlotte Haug, MD, […]
Physicians Avoid Recommending HPV Vaccine in Girls Aged 11 to 12 Years
By: Fran Lowry From Medscape Medical News August 4, 2010 — The majority of pediatricians and family physicians in the United States are offering the human papillomavirus (HPV) vaccine to their older adolescent patients, but fewer are recommending the vaccine to their younger patients (those aged 11 to 12 years) — the age group that […]
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