Toshiyuki Sasagawa, Walid Basha, Hiroshi Yamazaki, and Masaki Inoue Abstract To estimate the risk of human papillomavirus (HPV) infection for cervical malignancies, we conducted a case-control study in Japan. Abnormal cervical cell (366) and normal cell samples (1562) were tested for the presence of HPV DNA using a new PCR-based test (LCR-E7 PCR). When single […]
Human papillomavirus (HPV) type distribution in cervical carcinoma, low-grade, and high-grade squamous intraepithelial lesions in Venezuelan women.
Correnti M, Medina F, Cavazza ME, Rennola A, Avila M, Fernándes A. Abstract OBJECTIVE: Cervical cancer is an important cause of mortality among women in developing countries, especially in the Latin America and Caribbean (LAC) region. Infection with high-risk (HR) human papillomavirus (HPV) has been identified as the primary cause of cervical cancer. The aim […]
AS04-Adjuvanted Human Papillomavirus (HPV) Types 16 and 18 Vaccine (Cervarix®): A Review of its Use in the Prevention of Premalignant Cervical Lesions and Cervical Cancer Causally Related to Certain Oncogenic HPV Types
McKeage K, Romanowski B; Drugs 71 (4), 465-8 (Mar 2011) The AS04-adjuvanted human papillomavirus (HPV) 16/18 vaccine (Cervarix®) is a noninfectious recombinant vaccine produced using purified virus-like particles (VLPs) that induce a strong immunogenic response eliciting high levels of anti-L1 VLP antibodies that persist at levels markedly greater than those observed with natural infection. The […]
Impact of Improved Classification on the Association of Human Papillomavirus
Philip E. Castle*, Mark Schiffman, Cosette M. Wheeler, Nicolas Wentzensen, and Patti E. Gravitt Initially submitted June 1, 2009; accepted for publication August 5, 2009. Correspondence to Dr. Philip E. Castle, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard, Room 5004, MSC 7234, Bethesda, MD 20892-7234 (e-mail: castlep@mail.nih.gov). Misclassification of exposure […]
Best Practices for Health Care Professionals on the use of Polymerase Chain Reaction (PCR) for Diagnosing Pertussis
Published by the CDC With the continuing resurgence of pertussis, health care professionals will see more patients with suspected pertussis. Polymerase Chain Reaction (PCR) is an important tool for timely diagnosis of pertussis and is increasingly available to clinicians. PCR is a molecular technique used to detect DNA sequences of the Bordetella pertussis bacterium and […]
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