Insight into the cellular fate and toxicity of aluminium adjuvants used in clinically approved human vaccinations Matthew Mold,1 Emma Shardlow,1 and Christopher Exleya,1 Author information ► Article notes ► Copyright and License information ► Abstract Aluminium adjuvants remain the most widely used and effective adjuvants in vaccination and immunotherapy. Herein, the particle size distribution (PSD) […]
Biopersistence and brain translocation of aluminum adjuvants of vaccines
Authors: Romain Kroum Gherardi*, Housam Eidi, Guillemette Crépeaux, François Jerome Authier and Josette Cadusseau Aluminum oxyhydroxide (alum) is a crystalline compound widely used as an immunological adjuvant of vaccines. Concerns linked to the use of alum particles emerged following recognition of their causative role in the so-called macrophagic myofasciitis (MMF) lesion detected in patients with myalgic […]
Behavioral abnormalities in young female mice
Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil. Authors: Inbar R1, Weiss R2, Tomljenovic L3, Arango MT4, Deri Y5, Shaw CA6, Chapman J7, Blank M5, Shoenfeld Y8 Abstract Vaccine adjuvants and vaccines may induce autoimmune and inflammatory manifestations in susceptible individuals. To date most human vaccine […]
Vaccine adjuvants: Current state and future trends
Future Trends Authors: Nikolai Petrovsky1 and Julio César Aguilar2 Abstract The problem with pure recombinant or synthetic antigens used in modern day vaccines is that they are generally far less immunogenic than older style live or killed whole organism vaccines. This has created a major need for improved and more powerful adjuvants for use in these vaccines. With […]
Etiology of autism spectrum disorders: Genes, environment, or both?
Autism Authors: C Shaw, S Sheth, D Li, L Tomljenovic Abstract Introduction Thus far, most of the research on both neurodevelopmental and neurodegenerative disorders has been focused on finding the presumed underlying genetic causes, while much less emphasis has been put on potential environmental factors. While some forms of autism are clearly genetic, the fact remains […]
- 1
- 2
- 3
- …
- 5
- Next Page »
