Authors: Jennifer A. Groner1, George D. Harris2 and Diane M. Harper3,4,5 TO THE EDITOR—The recent Centers for Disease Control and Prevention (CDC) study by Markowitz et al [1] provides limited and inconclusive data on 111 sexually active females between 14 and 19 years of age who received at least 1 dose of quadrivalent human papillomavirus vaccine (HPV4). The […]
Human papillomavirus (HPV) is not the main cause of preinvasive and invasive cervical cancer among patients in Delta Region, Egypt
Human papillomavirus (HPV) is not the main cause of preinvasive and invasive cervical cancer among patients in Delta Region, Egypt Authors: Thabet M, Hemida R, Hasan M, Elshamy M, Elfaraash M, Emam M. Abstract BACKGROUND: Cervical cancer remains a significant problem worldwide particularly in underdeveloped countries. It is necessary to have a persistent infection of the […]
Human Papillomavirus in Infants: Transmission, HPV Prevalence, and Persistence
HPV Prevalence, and Persistence Author: Delese E. LaCour, MD* Introduction HPV prevalence. Infections caused by human papillomavirus (HPV) result in considerable morbidity and mortality throughout the world.1–4 Conditions such as anogenital warts, caused by low-risk HPV genotypes and cervical dysplasia, more commonly caused by oncogenic HPV types, can affect females in all age groups.5–9 The prevalence […]
Reduction in HPV prevalence?
[SaneVax: Following is an excerpt from a letter to the editor of The Journal of Infectious Diseases that provides a critique of a scientific study used to demonstrate the success of HPV vaccination programs in the United States. Evidently, things are not so cut and dried as the CDC would like us to believe.] Reduction in HPV Prevalence—No […]
HPV prevalence and genetic predisposition to cervical cancer in Saudi Arabia
Genetic Predisposition Corresponding author: Ghazi Alsbeih galsbeih@kfshrc.edu.sa Background Cervical cancer incidence is low in Saudi Arabian women, suggesting low prevalence to HPV infection due to environmental, cultural and genetic differences. Therefore, we investigated HPV prevalence and genotype distribution in cervical cancer as well as the association with 9 genetic single nucleotide polymorphisms (SNPs): CDKN1A (p21) C31A, TP53 C72G, ATM G1853A, HDM2promoter T309G, HDM2 A110G, LIG4 A591G, XRCC1 G399A, XRCC3 C241T and TGFβ1 T10C, […]