J Inorg Biochem. 2009 Nov;103(11):1571-8. Epub 2009 Aug 20. Couette M, Boisse MF, Maison P, Brugieres P, Cesaro P, Chevalier X, Gherardi RK, Bachoud-Levi AC, Authier FJ. Abstract Macrophagic myofasciitis (MMF) is an emerging condition, characterized by specific muscle lesions assessing long-term persistence of aluminum hydroxide within macrophages at the site of previous immunization. Affected […]
Macrophagic myofasciitis lesions assess long-term persistence of vaccine-derived aluminum hydroxide in muscle
Macrophagic myofasciitis (MMF) is an emerging condition of unknown cause, detected in patients with diffuse arthromyalgias and fatigue, and characterized by muscle infiltration by granular periodic acid-Schiff’s reagent-positive macrophages and lymphocytes. Itrracytoplasmic inclusions have been observed in macrophages of some patients….. We conclude that the MMF lesion is secondary to intramuscular injection of aluminum hydroxide-containing […]
Aluminum adjuvant linked to Gulf War Illness induces motor neuron death in mice
Michael S. Petrik, Margaret C. Wong, Rena C. Tabata, Robert F. Garry and Christopher A. Shaw Abstract Gulf War illness (GWI) affects a significant percentage of veterans of the 1991 conflict, but its origin remains unknown. Associated with some cases of GWI are increased incidences of amyotrophic lateral sclerosis and other neurological disorders. Whereas many […]
New-Age Vaccine Adjuvants: Friend or Foe?
By: Nikolai Petrovsky, Susanne Heinzel, Yoshikazu Honda, and A. Bruce Lyons A major unsolved challenge in development is how to achieve a potent adjuvant effect while avoiding reactogenicity or toxicity. Older vaccines made from live or killed whole organisms were effective, but suffered from high reactogenicity. As vaccine manufacturers developed safer, less reactogenic subunit vaccines, […]
Aluminum Hydroxide Injections Lead to Motor Deficits and Motor Neuron Degeneration
Authors: Christopher Shaw/Michael Petrik 10 Feb 2010 Abstract: Gulf War Syndrome is a multi-system disorder afflicting many veterans of Western armies in the 1990–1991 Gulf War. A number of those afflicted may show neurological deficits including various cognitive dysfunctions and motor neuron disease, the latter expression virtually indistinguishable from classical amyotrophic lateral sclerosis (ALS) except […]
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