Intracellular Aluminium Adjuvant Authors: Matthew Mold, Håkan Eriksson, Peter Siesjö, Anna Darabi, Emma Shardlow & Christopher Exley Abstract Aluminium-based adjuvants (ABA) are the predominant adjuvants used in human vaccinations. While a consensus is yet to be reached on the aetiology of the biological activities of ABA several studies have identified shape, crystallinity and size as critical factors affecting their adjuvanticity. In […]
Mechanisms of aluminum adjuvant toxicity and autoimmunity in pediatric populations
Aluminum Adjuvant Toxicity Tomljenovic L1, Shaw CA. Abstract Immune challenges during early development, including those vaccine-induced, can lead to permanent detrimental alterations of the brain and immune function. Experimental evidence also shows that simultaneous administration of as little as two to three immune adjuvants can overcome genetic resistance to autoimmunity. In some developed countries, by […]
Acute Disseminated Encephalomyelitis Onset: Evaluation Based on Vaccine Adverse Events Reporting Systems
Acute Disseminated Encephalomyelitis Acute Disseminated Encephalomyelitis… Pellegrino P, Carnovale C, Perrone V, Pozzi M, Antoniazzi S, Clementi E, Radice S. Author information Abstract OBJECTIVE: To evaluate epidemiological features of post vaccine acute disseminated encephalomyelitis (ADEM) by considering data from different pharmacovigilance surveillance systems. METHODS: The Vaccine Adverse Event Reporting System (VAERS) database and the EudraVigilance post-authorisation module (EVPM) were searched to […]
What is ASIA? An interview with Yehuda Shoenfeld
Yehuda Shoenfeld By Yehuda Shoenfeld, Sheba Medical Center Abstract In this Q&A, we talk to Professor Yehuda Shoenfeld about Autoimmune Syndrome Induced by Adjuvants (ASIA) and discuss his recommendations regarding further research in the field. Professor Yehuda Shoenfeld talks about ASIA (‘autoimmune syndrome induced by adjuvants’) Introduction Professor Yehuda Shoenfeld is the founder and head […]
Human Papilloma Virus Vaccine and Primary Ovarian Failure: Another Facet of the Autoimmune/Inflammatory Syndrome Induced by Adjuvants.
Primary Ovarian Failure Colafrancesco S • Perricone C • Tomljenovic L • Shoenfeld Y Source Zabludowicz Center for Autoimmune Diseases Sheba Medical Center, Tel-Hashomer, Israel; Rheumatology Unit, Department of Internal Medicine and Medical Specialities, Sapienza University of Rome, Rome, Italy. Abstract PROBLEM: Post-vaccination autoimmune phenomena are a major facet of the autoimmune/inflammatory syndrome induced by […]
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