Immunological studies of cerebrospinal fluid from patients with CNS symptoms after human papillomavirus vaccination Highlights •32 patients with prolonged CNS symptoms after HPV vaccination were studied. •CSF levels of IL-4, IL-13, IL-17, IL-8 and MCP-1 were elevated. •CSF levels of PDGF-bb and IL-12 were decreased. •Antibodies to GluN2B-NT2, GluN2B-CT and GluN1-NT in CSF were increased. […]
Severe somatoform and dysautonomic syndromes after HPV vaccination: case series and review of literature
Somatoform and Sysautonomic Syndromes Authors: Beniamino Palmieri; Dimitri Poddighe; Maria Vadalà; Carmen Laurino; Carla Carnovale; Emilio Clementi Abstract: Human papilloma virus (HPV) is recognized as a major cause for cervical cancer among women worldwide. Two HPV vaccines are currently available: Gardasil® and Cervarix®. Both vaccines enclose viral antigenic proteins, but differ as to the biological systems of culture and the adjuvant components. Recently, a collection […]
Quadrivalent human papillomavirus vaccine and autoimmune adverse events: a case–control assessment of the vaccine adverse event reporting system (VAERS) database
Quadrivalent human papillomavirus vaccine and autoimmune adverse events: a case–control assessment of the vaccine adverse event reporting system (VAERS) database Authors: David A. Geier, Mark R. Geier Abstract: Gardasil is a quadrivalent human papillomavirus (HPV4) vaccine that was approved for use by the US Food and Drug Administration in June 2006. HPV4 vaccine is routinely recommended […]
Behavioral abnormalities in young female mice
Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil. Authors: Inbar R1, Weiss R2, Tomljenovic L3, Arango MT4, Deri Y5, Shaw CA6, Chapman J7, Blank M5, Shoenfeld Y8 Abstract Vaccine adjuvants and vaccines may induce autoimmune and inflammatory manifestations in susceptible individuals. To date most human vaccine […]
CNS demyelination and quadrivalent HPV vaccination
CNS demyelination and quadrivalent HPV vaccination report: Authors: Sutton I1, Lahoria R, Tan I, Clouston P, Barnett M. Abstract Vaccination is generally considered safe in patients with multiple sclerosis (MS). We report five patients who presented with multifocal or atypical demyelinating syndromes within 21 days of immunization with the quadrivalent human papilloma virus (HPV) vaccine, Gardasil. […]
