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New Quality-Control Investigations on Vaccines: Micro- and Nanocontamination

October 10, 2018 By admin

Authors: Antonietta M. Gatti and Stefano Montanari Abstract Vaccines are being under investigation for the possible side effects they can cause. In order to supply new information, an electron-microscopy investigation method was applied to the study of vaccines, aimed at verifying the presence of solid contaminants by means of an Environmental Scanning Electron Microscope equipped with […]

Filed Under: Italy, Vaccine Safety, Vaccines Tagged With: Biocompatibility, contamination, immunogenicity, nanoparticles, toxicity, vaccines

Nanoparticulate systems for brain delivery of drugs.

March 15, 2011 By admin

Kreuter J. Institut für Pharmazeutische Technologie, Biozentrum, J.W.Goethe-Universität, D-60439 Frankfurt, Germany. kreuter@em.uni-frankfurt.de Abstract The blood–brain barrier (BBB) represents an insurmountable obstacle for a large number of drugs, including antibiotics, antineoplastic agents, and a variety of central nervous system (CNS)-active drugs, especially neuropeptides. One of the possibilities to overcome this barrier is a drug delivery to […]

Filed Under: Polysorbates Tagged With: drug delivery to the brain, nanoparticles

Polysorbate-80 coating enhances uptake of polybutylcyanoacrylate (PBCA)-nanoparticles by human and bovine primary brain capillary endothelial cells.

March 15, 2011 By admin

Ramge P, Unger RE, Oltrogge JB, Zenker D, Begley D, Kreuter J, Von Briesen H. Eur J Neurosci. 2000 Jun;12(6):1931-40. Abstract Certain drugs such as dalargin, loperamide or tubocurarine are not transported across the blood-brain barrier (BBB) and therefore exhibit no effects on the central nervous system. However, effects on the central nervous system can […]

Filed Under: Polysorbates Tagged With: blood brain barrier, nanoparticles, polysorbate 80

Nano-sized Vaccines

March 7, 2011 By admin Leave a Comment

MIT engineers have designed a new type of nanoparticle that could safely and effectively deliver vaccines for diseases such as HIV and malaria. The new particles, described in the Feb. 20 issue of Nature Materials, consist of concentric fatty spheres that can carry synthetic versions of proteins normally produced by viruses. These synthetic particles elicit […]

Filed Under: Vaccine Science Tagged With: nanoparticles, vaccine research

Virus-mimic 'paves way for vaccine'

February 26, 2011 By admin Leave a Comment

From The Press Association Artificial particles which resemble virus material could form the basis of super-efficient vaccines, new research has suggested. The nanoparticles have already been used to protect mice and monkeys against flu. Scientists now hope to develop hybrid natural-synthetic vaccines that can prevent serious infections for a lifetime. The experimental vaccine consists of […]

Filed Under: Vaccine Science, Vaccines Tagged With: nanoparticles, new vaccines, virus-mimic

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This Week’s Survivor

Celia from Madrid

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HPV Vaccine VAERS Reports

Description 12/14/2019  TOTAL
Disabled 3,092
Deaths 523
Did Not Recover 13,072
Abnormal Smear 695
Cervical Cancer 186
Infertility 52
Life-threatening 1,001
Emergency Room 15,419
Hospitalized 6,448
Extended Hosp. Stay 304
Serious 9,497
Total Adverse Events 64,270

Access expanded report here.

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