Oncology Stats Elsevier Global Medical News. 2011 Aug 4, B Jancin The skin may hold the key to differentiating classic pemphigus from the heterogenous autoimmune syndrome known as paraneoplastic autoimmune multiorgan syndrome. It is a distinction of critical prognostic importance, because paraneoplastic autoimmune multiorgan syndrome (PAMS) typically is rapidly fatal, according to Dr. Sergei A. […]
Investigating Viruses in Cells Used to Make Vaccines; and Evaluating the Potential Threat Posed by Transmission of Viruses to Humans
FDA Vaccines Blood & Biologics Principal Investigator: Arifa S. Khan, PhD Office / Division / Lab: OVRR / DVP / LR General Overview The emergence of pathogenic virus infections like influenza and HIV have created an urgent need for new vaccines. Virus-based vaccines are made in living cells (cell substrates). Some manufacturers are investigating the […]
Adventitious Agents and Vaccines
CDC Emerging Infectious Diseases Panel Summary from the 2000 Emerging Infectious Diseases Conference in Atlanta, Georgia Philip R. Krause Food and Drug Administration, Bethesda, Maryland, USA A discussion of adventitious agents and vaccines is pertinent in the context of emerging infectious diseases. Many novel vaccines are produced in animal cell substrates, and emerging infectious diseases […]
Attitudes toward HPV Vaccination among Women Aged 27 to 45.
Pub Med SRN Obstet Gynecol.2011;2011:670318. Epub 2011 Apr 7. Weiss TW, Rosenthal SL, Zimet GD. Source Global Health Outcomes, Merck & Co., Inc., P.O. Box 4, WP97-A243, 770 Sumneytown Pike, West Point, PA 19486-0004, USA. Abstract The purpose of this study was to identify attitudes toward HPV vaccination among US women 27 to 45 years […]
DNA released from dying host cells mediates aluminum adjuvant activity
Nature Medicine (2011)doi:10.1038/nm.2403 Received: 11 February 2011 Accepted: 19 May 2011 Published online: 17 July 2011 Abstract Aluminum-based adjuvants (aluminum salts or alum) are widely used in human vaccination, although their mechanisms of action are poorly understood. Here we report that, in mice, alum causes cell death and the subsequent release of host cell […]
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