Insight into the cellular fate and toxicity of aluminium adjuvants used in clinically approved human vaccinations Matthew Mold,1 Emma Shardlow,1 and Christopher Exleya,1 Author information ► Article notes ► Copyright and License information ► Abstract Aluminium adjuvants remain the most widely used and effective adjuvants in vaccination and immunotherapy. Herein, the particle size distribution (PSD) […]
Quadrivalent human papillomavirus vaccine and autoimmune adverse events: a case–control assessment of the vaccine adverse event reporting system (VAERS) database
Quadrivalent human papillomavirus vaccine and autoimmune adverse events: a case–control assessment of the vaccine adverse event reporting system (VAERS) database Authors: David A. Geier, Mark R. Geier Abstract: Gardasil is a quadrivalent human papillomavirus (HPV4) vaccine that was approved for use by the US Food and Drug Administration in June 2006. HPV4 vaccine is routinely recommended […]
Biopersistence and brain translocation of aluminum adjuvants of vaccines
Authors: Romain Kroum Gherardi*, Housam Eidi, Guillemette Crépeaux, François Jerome Authier and Josette Cadusseau Aluminum oxyhydroxide (alum) is a crystalline compound widely used as an immunological adjuvant of vaccines. Concerns linked to the use of alum particles emerged following recognition of their causative role in the so-called macrophagic myofasciitis (MMF) lesion detected in patients with myalgic […]
Behavioral abnormalities in young female mice
Behavioral abnormalities in young female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil. Authors: Inbar R1, Weiss R2, Tomljenovic L3, Arango MT4, Deri Y5, Shaw CA6, Chapman J7, Blank M5, Shoenfeld Y8 Abstract Vaccine adjuvants and vaccines may induce autoimmune and inflammatory manifestations in susceptible individuals. To date most human vaccine […]
Postural Orthostatic Tachycardia Syndrome (POTS) – A novel member of the autoimmune family
Postural Orthostatic Tachycardia Syndrome (POTS) Authors: S Dahan, L Tomljenovic, Y Shoenfeld Abstract Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous disorder of the autonomic nervous system in which a change from the supine position to an upright position causes an abnormally large increase in heart rate or tachycardia (30 bpm within 10 min of standing or head-up […]
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