Authors: Rodrigo Covre Vieira1*, Jeniffer do Socorro Valente Monteiro2, Estéfane Primo Manso2, Maria Renata Mendonça dos Santos3, Mihoko Yamamoto Tsutsumi4, Edna Aoba Yassui Ishikawa1, Stephen Francis Ferrari5,Karla Valéria Batista Lima6 and Maísa Silva de Sousa1 Abstract Background Human papillomavirus (HPV) infection is associated with cervical cancer, the most frequent cancer in women from northern Brazil. Assessment […]
Vitamin D Levels, Antibody Titers Produced in Response
Do Vitamin D Levels Affect Antibody Titers Produced in Response to HPV Vaccine? Antibody Titers Produced in Response Authors: Zimmerman RK1, Lin CJ, Raviotta JM, Nowalk MP. Abstract In addition to its well-known effects on bone metabolism, vitamin D is an immunomodulating hormone. Serum vitamin D levels in males 18-25 years were measured at baseline, and HPV […]
Vaccine adjuvants: Current state and future trends
Future Trends Authors: Nikolai Petrovsky1 and Julio César Aguilar2 Abstract The problem with pure recombinant or synthetic antigens used in modern day vaccines is that they are generally far less immunogenic than older style live or killed whole organism vaccines. This has created a major need for improved and more powerful adjuvants for use in these vaccines. With […]
Polysorbate 80 in medical products and nonimmunologic anaphylactoid reactions
Authors: Coors EA1, Seybold H, Merk HF, Mahler V. Abstract BACKGROUND: Polyoxyethylene-sorbitan-20-monooleate (also known as polysorbate 80 and Tween 80) is a solubilizing agent ubiquitously used in nutritives, creams, ointments, lotions, and multiple medical preparations (e.g., vitamin oils, vaccines, and anticancer agents) and as an additive in tablets. Whereas its relevance as a contact allergen has […]
Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind
Molecular variants of human papillomavirus type 16 from four continents suggest ancient pandemic spread of the virus and its coevolution with humankind Authors: S Y Chan, L Ho, C K Ong, V Chow, B Drescher, M Dürst, J ter Meulen, L Villa, J Luande, H N Mgaya Abstract We have amplified by the polymerase chain reaction, […]
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